Excel 2010: Excel HyperLinks to images open in Internet Explorer Rather than Default App.

This issue can be annoying, it requires the registry to fix, all the normal rules apply when editing the registry.

1. Run  regedit.exe
2. Navigate to HKEY_CLASSES_ROOT -> jpegfile -> CLSID
3. Right-click on “Default” (the Value Name) and select “Modify”
4. Change “Value data” from {25336920-03F9-11cf-8FD0-00AA00686F13} to {FFE2A43C-56B9-4bf5-9A79-CC6D4285608A}